A Sustainable Green Enzymatic Method for Amide Bond Formation
نویسندگان
چکیده
A sustainable enzymatic strategy for the preparation of amides by using Candida antarctica lipase B as biocatalyst and cyclopentyl methyl ether a green safe solvent was devised. The method is simple efficient it produces with excellent conversions yields without need intensive purification steps. scope reaction extended to 28 diverse four different free carboxylic acids seven primary secondary amines, including cyclic amines. This methodology has potential become industrially reliable process direct amide synthesis.
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ژورنال
عنوان ژورنال: Molecules
سال: 2023
ISSN: ['1420-3049']
DOI: https://doi.org/10.3390/molecules28155706